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ISBER Working Groups
Biospecimen Science
Organizer:
Fay Betsou
Biospecimens stored in biorepositories are intended to be used for biomarker
identification and validation. The performance of such biomarkers greatly
depends on the pre-analytical variations of the samples having been used for its
initial identification. Quality Assurance on this issue is therefore of the
outmost importance and allows us to establish the right correspondence between
processing methods and end-use biomarkers. Interaction with OBBR and related FP7
initiatives should be ensured, in order to avoid duplication of efforts and for
the seek of consistency.
Issues
1. Selection of biospecimen quality assurance schemes
2. Identification of biospecimen handling critical points
3. Adaptation to downstream analysis formats
Outcomes
Edition of an annex to the next edition of ISBER Best Practices on
Biospecimen Preanalytics for Biorepositories.
Papers:
ISBER Biospecimen Science Working Group Literature Compilation
From Biospecimen
Logistics to Biospecimen Science (PDF)
The ISBER Biospecimen Science Working Group
published the following papers in Cancer Epidemiology, Biomarkers & Prevention:
Human Biospecimen Research: Experimental Protocol and Quality Control Tools
Fotini Betsou, Rebecca Barnes, Thomas Burke, Domenico Coppola, Yvonne DeSouza,
James Eliason, Barbara Glazer, David Horsfall, Cynthia Kleeberger, Sylvain
Lehmann, Anil Prasad, Amy Skubitz, Stella Somiari, Elaine Gunter, and
[International Society for Biological and Environmental Repositories (ISBER)
Working Group on Biospecimen Science
Betsou et al. Cancer Epidemiol
Biomarkers Prev.2009; 18: 1017-1025
Standard Preanalytical Coding for Biospecimens: Defining the Sample
PREanalytical Code
Fotini Betsou,
Sylvain Lehmann,
Garry Ashton,
Michael Barnes,
Erica E. Benson,
Domenico Coppola,
Yvonne DeSouza,
James Eliason,
Barbara Glazer,
Fiorella Guadagni,
Keith Harding,
David J. Horsfall,
Cynthia Kleeberger,
Umberto Nanni,
Anil Prasad,
Kathi Shea,
Amy Skubitz,
Stella Somiari,
Elaine Gunter,
and
International Society for Biological and
Environmental Repositories (ISBER) Working Group on Biospecimen
Science
Betsou et al.
Cancer Epidemiol Biomarkers Prev.
2010 Apr;19(4):1004-11. Epub 2010 Mar
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Repositories
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Email:
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